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Furthermore, our findings could reinforce the previously proven concept that AcM does not hydrolyze PGN of live bacteria, whilst leading to the indirect modulation of the microbiota, driven by the reduced protein availability in the caeca, with some measurable effects on the gene encoding PGN synthesis

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Glutamate exposure in rat hippocampal neurons triggers a sustained elevation of extracellular adenosine triphosphate (ATP) levels, subsequent activation of P2Y1 receptors (P2Y1R), and ultimately results in hippocampal neuron death [46]

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